While metformin has proven to be very effective, it’s also known that it’s positive effects tend to wear off over time. 25 percent of patients using metformin are then prescribed a “sulfonylureas” from the list above. The study showed reports, “…it was shown that the rate of death due to a heart attack or stroke was 2.5 times greater in the group taking tolbutamide (a sulfonylurea), than the group controlling their type 2 diabetes by diet alone.”
Another category of oral medications for type 2 diabetes are the “thiazolidinediones” which included well-known names like Actose, Rezulin, and Avandia. Rezuline was actually banned from the pharmaceutical market due to liver failure, but Avanda and Actose have resulted in significant negative side-effects as well.
From 42 different studies, Avandia was shown to actually increase risk of heart attack by 43 percent, with a 64 percent increase in risk of dying from heart disease when compared to other type 2 diabetics who were not given the drug. Actose, as well as Avandia, were both shown to cause weight gain.
The most troubling aspect of this report is simply the lack of proper studying performed before the drugs are available to the market. With pharmaceutical companies so eager to make a profit off the leading disease across the country, they’re putting their wallet ahead of their moral conscience.
More on this story here.
Eddie
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2 comments:
Its a bit of an oversimplification
I think.
Actos and Avandia should definitely only be given as a last resort but diet and exercise - particularly if the diet is the
'recommended diet' are not going to be the solution in every case.
With the sufonylureas it is far more likely to be the way in which they are prescribed which is so dangerous and failure to act on the effects.
If someone were to be constantly hypo-ing on these then insulin would probably not be the solution for them.
Diet and exercise should have been introduced from the beginning not when metformin appeared to stop being effective. In cases where weight loss is not an issue metformin doesn't do much, if anything anyway.
Some types of diabetes - for example MODY can be successfully controlled by sulfonylureas for years and others never progress.
Of course we would all prefer not to take any medication at all if we could avoid it.
If you are fortunate enough to get the right advice from the start - or more importantly avoid the wrong advice this is an option - sadly this isn't always the case.
Kath
Medication for diabetes with the least side effects varies from patient to patient; a doctor's consultation is important even if you know about the medication with the least side effects. You can refer to this article to know the medication names that may have the least side effect. Wrong diabetes medications can raise a high health risk, so avoid taking random medication for diabetes.
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